First Avenue is a major north-south thoroughfare on the East Side of Manhattan, New York City, stretching from the East Village to Harlem. It plays a vital role in the city’s urban fabric, connecting residential neighborhoods, hospitals, schools, parks, and cultural sites. This list of places in First Avenue includes well-known medical institutions, historical landmarks, government buildings, and local businesses. Whether you’re exploring the neighborhoods of the Lower East Side, Midtown East, or East Harlem, First Avenue features a wide array of notable locations that highlight the diversity and depth of Manhattan’s East Side.
Popular spots along First Avenue include the NYU Langone Medical Center, United Nations Headquarters (near First Avenue), Memorial Sloan Kettering Cancer Center, and more. From residential developments to civic spaces and cultural sites, this guide captures the essential places in First Avenue, Manhattan, New York City.
List of Places on First Avenue, Manhattan, New York City
0–9
- First Avenue station (BMT Canarsie Line)
- 14th Street station (IRT Second Avenue Line)
- 19th Street station (IRT Second Avenue Line)
- 50 United Nations Plaza
- 333 East 38th Street
- 1199 Plaza
B
- Beekman Tower
- Bellevue Hospital
C
- The Charles
- Church Center for the United Nations
- The Corinthian (Manhattan)
D
- Dag Hammarskjöld Library
- Dag Hammarskjöld Plaza
- Dangerfield’s
E
- East Side Airline Terminal
- East Village Radio
- Edgar J. Kaufmann Conference Center
- Eighth Street station (IRT Second Avenue Line)
- Enid A. Haupt Glass Garden
F
- First Street station (IRT Second Avenue Line)
H
- Hunter-Bellevue School of Nursing
I
- Isaacs Houses
J
- James Ewing Hospital
K
- Kips Bay Brewing Company
- Kips Bay Generating Station
- Kips Bay Towers
L
- Lanza’s
- Lucien (restaurant)
M
- M15 (New York City bus)
- Manhattan Place
- Maxwell’s Plum
- Metropolitan Hospital Center
- Metropolitan Park (Manhattan)
N
- New York University College of Dentistry
- NYU Langone Health
O
- One United Nations Plaza
P
- P.S. 135
- Patsy’s Pizzeria
- Performance Space New York
R
- Ralph Bunche Park
- Robert F. Wagner Houses
- Robert Moses Playground
- Rusk Institute of Rehabilitation Medicine
S
- Church of St. John Nepomucene
- St. John the Evangelist Church (Manhattan)
- St. Vartan Park
- Sushi Seki
T
- The Copper (building)
- Theater for the New City
- Thomas Jefferson Park
- Three United Nations Plaza
- Trump World Tower
- Trygve Lie Plaza
- Turkish House
- Two United Nations Plaza
U
- United Engineering Center
- United Nations General Assembly Building
- United Nations Secretariat Building
- United States Mission to the United Nations
V
- View 34
W
- Waterside Generating Station
- Willis Avenue Bridge
